Thursday, January 23, 2020

Coronavirus-related stocks


Cases of a novel pneumonia-like viral illness that originated in Wuhan, China in December have now been confirmed in South Korea, Thailand, Japan, Taiwan, Macau, and the U.S.
The genetic sequence of the new coronavirus, 2019-nCoV, is at least 70% similar to SARS-CoV.
  1. Inovio Pharma (INO) received new funding from the Coalition for Epidemic Preparedness Innovations or CEPI to develop vaccine against new coronavirus.  Collaborating with Beijing Advaccine Biotechnology Co. to advance the development in China of INO-4800 against the coronavirus and has already started preclinical testing and preparations for clinical product manufacturing.
  2. Moderna (MRNA) and CEPI, today announced a new collaboration to develop an mRNA vaccine against the novel coronavirus (2019-nCoV). 
  3. Alpha Pro Tech (APT) Canadian co. that manufactures masks and protective apparel 
  4. Lakeland Industries (LAKE) also produces protective clothes for high-risk workers,
  5. Co-Diagnostics (CODX) Utah company developing a test for the new coronavirus strain. 
  6. Vir Biotechnology (VIR) - Portfolio includes an antibody for another coronavirus strain. Company is in discussions with manufacturers and regulators regarding expediting the manufacture and regulatory pathway for any potential therapy,
  7. BioCryst (BCRX) - has a candidate in a Phase 1 study for a range of viruses
  8. Novavax (NVAX) - has launched a program for the Wuhan-coronavirus vaccine. It already boasts success in vaccine development for the MERS and SARS strains.
  9. NanoViricides (NNVC) - produces nan-medicines to fight virus such as swine flu and bird flu. It also has early-stage programs for Dengue viruses and Ebola and once dabbled in a MERS candidate.
  10. Cleveland BioLabs (CBLI) - develops immune-receptor activators.
  11. Cerus (CERS) - uses proprietary technology to inactivate the SARS strain.
  12. Aethlon Medical (AEMD) -  treats viral infections with its hemopurifier.
  13. AstraZeneca (AZN) - awaits direction from the World Health Organization before acting.
  14. Meridian Bioscience (VIVO) - diagnostic laboratories in China are using Meridian's Lyo-Ready 1-Step RT-qPCR Mix to develop fast and accurate screening. 
  15. AbbVie (ABBV) - China is using AbbVie’s HIV drugs to treat coronavirus A combination of lopinavir and ritonavir, sold under the brand name Kaletra. In some countries, Kaletra is sold as Aluvia.
  16. Gilead Sciences (GILD) - Feb. 3:  Company formalized an agreement with Chinese authorities to study the effectiveness of an experimental Ebola and SARS treatment. Feb. 1, 20: Gilead Sciences said it is sending an experimental antiviral drug to China for emergency treatment of coronavirus patients as well as testing to see if it works against the virus. There was an earlier report suggesting Gilead Sciences (GILD) is assessing using an Ebola drug for treatment of the coronavirus.
  17. Johnson & Johnson (JNJ) - Announced launch of multi-pronged response to the coronavirus outbreak:  JNJ is mobilizing resources at its Janssen Pharmaceutical Companies to launch a multi-pronged response to the coronavirus outbreak. The company has initiated efforts to develop a vaccine candidate against 2019-nCoV and broadly collaborate with others to screen a library of antiviral therapies.
  18. Sorrento Therapeutics (SRNE) - Announced manufacturing collaboration with Celularity to initiate emergency allogeneic NK cell therapy development for coronavirus infection.
  19. ImmuCell (ICCC)
  20. Nabriva Therapeutics (NBRV)
  21. iBio (IBIO)
+Allied Healthcare Products (AHPI) - manufactures and markets respiratory products, including croup tents, respiratory disposable products, such as oxygen tubing products, facemasks, cannulas, and ventilator circuits.

(by avg vol - 3 months)
                    

Wuhan seafood market pricelist where the virus reportedly originated

The first known cases in December 2019 were traced to an animal market in the Chinese city of Wuhan and are believed to have come from contact with live animals that were infected.
  • The Wuhan virus (officially referred to as 2019-nCoV) belongs to the coronavirus family, a category that includes Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) and that typically results in respiratory illnesses. While SARS and the new coronavirus are not identical, their similarities could make it easier to “cannibalize” prior research and start developing vaccines and therapeutics on an accelerated timeline.
  • Coronaviruses originate in animals — like camels, civets and bats — and are usually not transmissible to humans. But occasionally a coronavirus mutates and can pass from animals to humans and then from human to human, as was the case with the SARS epidemic in the early 2000s. 
  • SARS, which showed up in the early 2000s, infected more than 8,000 people and resulted in nearly 800 deaths. MERS, which appeared in the early 2010s, infected almost 2,500 people and led to more than 850 deaths.
  • Coronaviruses belong to a family known as Coronaviridae, and under an electron microscope they look like spiked rings. They're named for these spikes, which form a halo around their viral envelope.  
Coronavirus

China’s place in the global supply chain and concerns involving the coronavirus & the adverse impact it will have on economic growth and earnings growth.
The impact of the Wuhan coronavirus on China and perhaps the global economy will be a major focus as more updates pour in. The outbreak has already negatively impacted companies like IMAX (NYSE:IMAX), Yum China (NYSE:YUMC), Disney (NYSE:DIS), McDonald's (MCD), Luckin Coffee (NASDAQ:LK), China Eastern Airlines (NYSE:CEA), China Southern Airlines (NYSE:ZNH) and a large number of energy and travel stocks.

Efforts to contain the Wuhan virus are overlapping the important Chinese New Year holiday period, which means Macau casinos could see reduced traffic and lower gross gaming revenue for Wynn Resorts (NASDAQ:WYNN), MGM Resorts (NYSE:MGM), Galaxy Entertainment (OTCPK:GXYEF), SJM Holdings (OTCPK:SJMHF), Melco Resorts & Entertainment (NASDAQ:MLCO) and Studio City International (NYSE:MSC).

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