Friday, November 29, 2019

Market update (29 Nov 2019)

Nasdaq Composite +30.6% YTD
S&P 500 +25.3% YTD
Russell 2000 +20.5% YTD
Dow Jones Industrial Average +20.3% YTD

S&P 500 - 2 years

ETF composition - XBI - Biotech

Fund Name: SPDR® S&P® Biotech ETF
Ticker Symbol: XBI



Name Ticker % of net assets
1 Arrowhead Pharmaceuticals  ARWR 3.37
2 Medicines Company MDCO 2.57
3 Seattle Genetics Inc. SGEN 2.51
4 Intercept Pharmaceuticals Inc. ICPT 2.32
5 Alnylam Pharmaceuticals Inc ALNY 2.05
6 Regeneron Pharmaceuticals Inc. REGN 1.93
7 Sarepta Therapeutics Inc. SRPT 1.89
8 Biogen Inc. BIIB 1.87
9 Vertex Pharmaceuticals VRTX 1.84
10 AbbVie Inc. ABBV 1.83
11 Incyte Corporation INCY 1.80
12 Global Blood Therapeutics Inc GBT 1.79
13 Neurocrine Biosciences Inc. NBIX 1.79
14 Amgen Inc. AMGN 1.75
15 United Therapeutics Corporation UTHR 1.70
16 Mirati Therapeutics Inc. MRTX 1.70
17 Ligand Pharmaceuticals  LGND 1.69
18 Repligen Corporation RGEN 1.65
19 Biohaven Pharmaceutical BHVN 1.64
20 Spark Therapeutics Inc. ONCE 1.62
21 BioMarin Pharmaceutical Inc. BMRN 1.62
22 Alexion Pharmaceuticals Inc. ALXN 1.56
23 Amicus Therapeutics Inc. FOLD 1.54
24 Gilead Sciences Inc. GILD 1.48
25 Blueprint Medicines Corp. BPMC 1.43
26 Ionis Pharmaceuticals Inc. IONS 1.42
27 SAGE Therapeutics Inc. SAGE 1.38
28 Invitae Corp. NVTA 1.36
29 ACADIA Pharmaceuticals Inc. ACAD 1.31
30 Immunomedics Inc. IMMU 1.30
31 Exelixis Inc. EXEL 1.26
32 Iovance Biotherapeutics Inc IOVA 1.25
33 Insmed Incorporated INSM 1.18
34 FibroGen Inc. FGEN 1.14
35 bluebird bio Inc. BLUE 1.12
36 Exact Sciences Corporation EXAS 1.12
37 Esperion Therapeutics Inc. ESPR 1.10
38 REGENXBIO Inc. RGNX 1.10
39 Arena Pharmaceuticals Inc. ARNA 1.09
40 Portola Pharmaceuticals Inc. PTLA 1.09
41 Ra Pharmaceuticals Inc. RARX 1.03
42 Alkermes Plc ALKS 1.02
43 Agios Pharmaceuticals Inc. AGIO 1.02
44 CareDx Inc. CDNA 0.95
45 PTC Therapeutics Inc. PTCT 0.94
46 Adverum Biotechnologies Inc ADVM 0.92
47 ArQule Inc. ARQL 0.88
48 Ultragenyx Pharmaceutical Inc. RARE 0.87
49 Madrigal Pharmaceuticals Inc. MDGL 0.85
50 Myriad Genetics Inc. MYGN 0.83
51 Allakos Inc. ALLK 0.80
52 Natera Inc. NTRA 0.80
53 Veracyte Inc VCYT 0.77
54 Editas Medicine Inc. EDIT 0.76
55 Karyopharm Therapeutics Inc. KPTI 0.75
56 Ironwood Pharmaceuticals IRWD 0.73
57 Xencor Inc. XNCR 0.69
58 Halozyme Therapeutics Inc. HALO 0.68
59 Heron Therapeutics Inc HRTX 0.68
60 Emergent BioSolutions Inc. EBS 0.68
61 Sangamo Therapeutics Inc. SGMO 0.65
62 Coherus BioSciences Inc. CHRS 0.64
63 Enanta Pharmaceuticals Inc. ENTA 0.59
64 Acceleron Pharma Inc XLRN 0.54
65 Audentes Therapeutics Inc. BOLD 0.53
66 Fate Therapeutics Inc. FATE 0.53
67 Vanda Pharmaceuticals Inc. VNDA 0.53
68 Aimmune Therapeutics Inc AIMT 0.52
69 Atara Biotherapeutics Inc ATRA 0.51
70 Athenex Inc. ATNX 0.50
71 Epizyme Inc. EPZM 0.49
72 Puma Biotechnology Inc. PBYI 0.48
73 ZIOPHARM Oncology Inc. ZIOP 0.46
74 Viking Therapeutics Inc. VKTX 0.43
75 Vericel Corporation VCEL 0.43
76 Deciphera Pharmaceuticals Inc. DCPH 0.42
77 TG Therapeutics Inc. TGTX 0.41
78 Retrophin Inc. RTRX 0.40
79 Intellia Therapeutics Inc. NTLA 0.40
80 Dicerna Pharmaceuticals Inc. DRNA 0.39
81 Allogene Therapeutics Inc. ALLO 0.37
82 Apellis Pharmaceuticals Inc. APLS 0.37
83 Intrexon Corporation XON 0.35
84 Krystal Biotech Inc. KRYS 0.35
85 Radius Health Inc RDUS 0.32
86 Turning Point Therapeutics Inc. TPTX 0.32
87 Flexion Therapeutics Inc. FLXN 0.32
88 AMAG Pharmaceuticals Inc. AMAG 0.31
89 Anika Therapeutics Inc. ANIK 0.31
90 Eagle Pharmaceuticals Inc. EGRX 0.31
91 Momenta Pharmaceuticals Inc. MNTA 0.29
92 Voyager Therapeutics Inc. VYGR 0.29
93 Stemline Therapeutics Inc. STML 0.28
94 ImmunoGen Inc. IMGN 0.26
95 Spectrum Pharmaceuticals Inc. SPPI 0.25
96 Achillion Pharmaceuticals Inc. ACHN 0.24
97 G1 Therapeutics Inc. GTHX 0.24
98 Twist Bioscience Corp. TWST 0.24
99 Denali Therapeutics Inc. DNLI 0.22
100 OPKO Health Inc. OPK 0.22
101 Kura Oncology Inc. KURA 0.21
102 MacroGenics Inc. MGNX 0.20
103 Catalyst Pharmaceuticals Inc. CPRX 0.18
104 AnaptysBio Inc. ANAB 0.17
105 Akebia Therapeutics Inc. AKBA 0.16
106 Rocket Pharmaceuticals Inc. RCKT 0.16
107 BioCryst Pharmaceuticals Inc. BCRX 0.16
108 Cytokinetics Incorporated CYTK 0.15
109 Progenics Pharmaceuticals Inc. PGNX 0.15
110 Akcea Therapeutics Inc. AKCA 0.15
111 Rhythm Pharmaceuticals Inc. RYTM 0.14
112 Homology Medicines Inc. FIXX 0.12
113 AVROBIO Inc AVRO 0.11
114 Prothena Corp. Plc PRTA 0.11
115 CytomX Therapeutics Inc. CTMX 0.09

charts - ave vol (3 months)